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Figure 1 | Critical Care

Figure 1

From: Effect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability

Figure 1

Photomicrographs of the same subpleural alveoli on inflation and deflation. Alveoli of interest are outlined with black dots and depict the same alveolus at expiration and inspiration. Alveolar area at end-expiration (E) was subtracted from the area of the same alveolus at peak inspiration (I) to calculate the degree of alveolar instability (I-EΔ). Note that there is little change in alveolar size in the two dimensions that can be seen using our in vivo microscope during tidal ventilation.

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