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Table 4 Metabolisation of indocyanine green

From: Liver dysfunction after lung recruitment manoeuvres during pressure-controlled ventilation in experimental acute respiratory distress

 

Group

Tbaseline

TALI

T6 h

T18 h

PDR (%/minute)

PCV

9.7 (9.1–10.3)

11.3 (10.7–11.6)a

16.9 (13.2–18.2)a,b

14.7 (13.3–16.1)a,b

 

PCV+R

11.8 (10.6–12.9)

14.4 (12.5–17.4)a,c

15.4 (12.1–17.1)a

18.3 (13.6–20.7)a

CB (ml/minute)

PCV

322 (283–365)

421 (393–455)

512 (406–567)

477 (458–496)

 

PCV+R

477 (419–540)c

536 (456–664)

489 (461–510)

550 (469–625)

  1. Data are presented as the median (interquartile range). a,bFriedman repeated measures analysis of variance on rank with all pairwise multiple comparison procedures (Student-Newman-Keuls method): aversus Tbaseline, bversus TALI (p < 0.05). cMann-Whitney rank sum test: p < 0.05 versus PCV+R. CB, blood clearance of indocyanine green; PCV, pressure-controlled ventilation; PCV+R, pressure-controlled ventilation with recruitment manoeuvre; PDR, plasma disappearance rate of indocyanine green; T6 h, time point 6 hours after randomisation; T18 h, time point 18 hours after randomisation; TALI, time point after lung injury; Tbaseline, baseline time point.