From: Liver dysfunction associated with artificial nutrition in critically ill patients
TPN | EN | Total | p | |
---|---|---|---|---|
Number of patients | 303 | 422 | 725 | |
Women | 114 (38%) | 123 (29%) | 237 (33%) | 0.02 |
Age in years | 66 (48–73) | 61 (45–71) | 63 (47–72) | 0.01 |
APACHE II score | 17 (12–22) | 19 (13–23) | 18 (12–22) | 0.08 |
MODS | 5 (3–8) | 5 (3–7) | 5 (3–7) | 0.95 |
Primary diagnosis | 0.001 | |||
Gastrointestinal surgery | 145 | 33 | 178 | |
Respiratory failure | 21 | 112 | 133 | |
Stroke | 22 | 103 | 125 | |
Cardiovascular | 36 | 50 | 86 | |
Trauma | 19 | 64 | 83 | |
Infections in non-immunosuppressed patients | 18 | 22 | 40 | |
Infections in immunosuppressed patients | 4 | 7 | 11 | |
Metabolic diseases | 5 | 5 | 10 | |
Urology | 4 | 6 | 10 | |
Hematology | 7 | 2 | 9 | |
Poisoning | 4 | 4 | 8 | |
Obstetrics/Gynecology | 6 | 1 | 7 | |
AIDS | 1 | 1 | 2 | |
Other | 11 | 12 | 23 | |
Type of patients | 0.001 | |||
Medical | 105 | 257 | 362 | |
Surgical | 175 | 89 | 264 | |
Trauma | 23 | 76 | 99 | |
Sepsis on admission | 122 (40%) | 86 (20%) | 208 (29%) | 0.001 |
Septic shock on admission | 70 (23%) | 35 (8%) | 105 (15%) | 0.001 |
Patients on mechanical ventilation | 239 (79%) | 382 (91%) | 621 (86%) | 0.001 |
Days of mechanical ventilation | 7 (2–16) | 9 (4–17) | 8 (3–16) | 0.001 |
Intensive care unit length of stay in days | 8 (5–17) | 12 (7–21) | 10 (6–20) | 0.001 |
Hospital length of stay in days | 25 (15–29) | 25 (15–28) | 25 (15–29) | 0.6 |
Mortality at 28 days | 85 (28.1%) | 119 (28.2%) | 204 (28%) | 0.9 |