Figure 1From: Case report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationshipsPlasma R,S-, R-, and S-methadone concentrations (left y-axis) and naloxone infusion rate (right y-axis) versus time after ingestion of a 3.14-mg/kg single oral dose of the racemic R,S-methadone.Back to article page