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Table 2 Plasma clearance of cytokines

From: Effect of extracorporeal liver support by MARS and Prometheus on serum cytokines in acute-on-chronic liver failure

 

Molecular weight (kDa)

PlCl at 60 minutes (ml/minute)

  

MARSâ„¢

Prometheusâ„¢

IL-6

21–28

3 (-1; 6)

4 (2; 20)

IL-8

8–10

17 (0; 28)

3 (-1; 35)

IL-10

35–40

16 (5; 26)a

46 (19; 60)b

TNF-α

17

29 (-114; 31)

25 (-5; 47)

sTNF-αR1

55

2 (-2; 9)

12 (3; 16)

  1. ap < 0.05 versus IL-6; bp < 0.05 versus MARS. Values (ml/minute) are expressed as median (Q1; Q3). IL, interleukin; MARS, molecular adsorbent recirculating system; PlCl, plasma clearance; sTNF-αR1 = soluble tumor necrosis factor-alpha receptor 1; TNF-α = tumor necrosis factor-alpha.
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Critical Care

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