Parameter
|
Baseline, mean (SD)
|
Time point from baseline
|
---|
| |
1
|
2
|
3
|
4 (1 hour after treatment discontinuation)
|
---|
| |
Mean (SD)
|
Contrast with the baseline
|
Mean (SD)
|
Contrast with the baseline
|
Mean (SD)
|
Contrast with the baseline
|
Mean (SD)
|
Contrast with the baseline
|
---|
PaCO2 (mmHg)
|
71.7 (5.8)
|
58.5 (7.1)
|
p = 0.002
|
60.0 (5.9)
|
p < 0.0001
|
61.0 (7.9)
|
p = 0.03
|
70.1 (4.1)
|
p = 0.37
|
Cardiac output (l/min)
|
6.6 (0.9)
|
5.8 (1.2)
|
p = 0.32
|
5.7 (1.1)
|
p = 0.21
|
6.4 (1.7)
|
p = 0.82
|
5.8 (1.3)
|
p = 0.27
|
Temperature (°C)
|
38.5 (0.5)
|
38.1 (1.0)
|
p = 0.15
|
38.3 (1.2)
|
p = 0.68
|
37.8 (1.7)
|
p = 0.30
|
37.8 (1.5)
|
p = 0.27
|
- PaCO2, arterial partial pressure of carbon dioxide; SD, standard deviation.