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Table 2 Adrenal function according to the serum albumin level

From: Adrenal function testing in patients with septic shock

 

Albumin ≤ 2.5 g/dl (n = 75)

Albumin > 2.5 g/dl (n = 12)

P value

Baseline cortisol (μg/dl)

15.5 (10.4–23.4)

22.4 (15.5–26.7)

0.04*

Cortisol 60 (μg/dl)

23.5 (17.2–36.6)

40.3 (27–51.5)

0.009*

Cortisol 120 (μg/dl)

30.4 (23.2–46.7)

41.9 (33.1–54.9)

0.04*

Δmax1 (μg/dl)

6.9 (3.5–13.2)

13.2 (3.7–26.6)

0.24

Δmax249 (μg/dl)

14.5 (9.4–23.4)

18.8 (9.9–28.9)

0.48

Baseline cortisol ≤ 10

17 (22.7)

1 (8.3)

0.45

Baseline cortisol ≤ 15

37 (49.3)

3 (25)

0.12

Baseline cortisol ≤ 20

52 (69.3)

6 (50)

0.2

Baseline cortisol ≤ 23.6

58 (77.3)

6 (50)

0.07

Baseline cortisol ≤ 25

63 (84)

7 (58.3)

0.05*

Baseline cortisol ≤ 34

70 (93.3)

11 (91.7)

1.0

Δmax249 ≤ 9

18 (24)

3 (25)

1.0

Δmax1 ≤ 9

46 (61.3)

4 (33.3)

0.07

  1. Data presented as n (%) or median (interquartile range). Protein and albumin levels were not measured in 15 patients. Cortisol units: 1 μg/dl = 27.6 nmol/l. Cortisol 60, serum cortisol level drawn 60 minutes after stimulus with 1 μg corticotropin; Cortisol 120, serum cortisol level drawn 60 minutes after stimulus with 249 μg corticotropin (120 minutes after serum baseline cortisol); Δmax1, cortisol 60 value minus the baseline cortisol level; Δmax249, cortisol 120 value minus the baseline cortisol level.