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Table 1 Clinical, biological and infection data of patients

From: Adrenal function testing in patients with septic shock

Sex

 

   Female

59 (57.8)

   Male

43 (42.2)

Age (years)

74 (62–82)

Admission diagnoses

 

   Postoperative

47 (46.1)

   Medical

50 (49)

   Trauma

5 (4.9)

Acute respiratory distress syndrome

52 (51)

Length of intensive care unit stay (days)

18 (12–27.3)

Length of hospital stay (days)

33 (19–85.3)

Days for corticotropin testa

2 (1–4)

Total serum protein (g/dl)b

4.7 (4.1–5.2)

Serum albumin (g/dl)b

2 (1.7–2.4)

White blood cells (cells/μl)

11,550 (8,275–16,500)

C-reactive protein (mg/dl)

16.3 (10.5–25)

Baseline cortisol levels (μg/dl)

17.2 (10.6–23.8)

Cortisol 60 (μg/dl)

25.4 (18.6–39.2)

Cortisol 120 (μg/dl)

35.5 (24.5–49.9)

Δmax1 (μg/dl)

8.2 (3.5–17.3)

Δmax249 (μg/dl)

16.6 (10–26)

Mean daily dose of norepinephrinec (μg/kg/minute)

0.13 (0.04–0.54)

Sequential Organ Failure Assessment score (corticotropin test day)

9 (7.8–11)

Maximum Sequential Organ Failure Assessment score

10 (9–13)

First-day Sequential Organ Failure Assessment score

7 (4–10)

Acute Physiologic and Chronic Heath Evaluation II score

20 (17–23)

Simplified Acute Physiology II score

43.5 (36–52.3)

28-day mortality rate

32 (31.4)

Intensive care unit mortality rate

36 (35.3)

Hospital mortality rate

46 (45.1)

Site of infection

 

   ◦Intra-abdominal

28 (27.5)

   ◦Soft tissue abscess/cellulitis

3 (2.9)

   ◦Lung

58 (56.9)

   ◦Central nervous system

1 (1)

   ◦Urinary tract

10 (9.8)

   ◦Endovascular infection

2 (2)

Microorganismsd

 

   ◦Gram-negative bacillus

72 (61.6)

   ◦Gram-positive coccus

39 (33.3)

   ◦Fungus

6 (5.1)

Bacteremia

22 (21.6)

Type of infection

 

   ◦Community

51 (50)

   ◦Nosocomial

51 (50)

  1. Data presented as n (%) or median (interquartile range). Cortisol units: 1 μg/dl = 27.6 nmol/l. Cortisol 60, serum cortisol level drawn 60 minutes after stimulus with 1 μg corticotropin; Cortisol 120, serum cortisol level drawn 60 minutes after stimulus with 249 μg corticotropin (120 minutes after serum baseline cortisol); Δmax1, cortisol 60 value minus the baseline cortisol level; Δmax249, cortisol 120 value minus the baseline cortisol level. aDifference between corticotropin test day and intensive care unit admission day. bProtein and albumin levels were not measured in 15 patients. cMean daily dose of norepinephrine during the first five days after hydrocortisone usage or after the corticotropin test. dMicrobiological identification was obtained in 69 patients (67.6%).