Variable | Group | T1 | T2 | T3 | T4 | T5 | T6 |
---|---|---|---|---|---|---|---|
MPAP (mmHg) | Control | 18 ± 1 | 25 ± 1‡‡‡ | 26 ± 1 | 26 ± 1 | 26 ± 1 | 25 ± 1 |
AVP | 19 ± 1 | 27 ± 1‡‡‡ | 27 ± 2 | 27 ± 2 | 26 ± 2 | 27 ± 3 | |
AVP-Dobu | 20 ± 1 | 25 ± 1‡‡‡ | 25 ± 1 | 25 ± 1 | 25 ± 1 | 24 ± 1 | |
PVRI (dyne.s.cm-5·m2) | Control | 99 ± 8 | 138 ± 18‡ | 142 ± 14 | 145 ± 13 | 146 ± 11 | 140 ± 10 |
AVP | 98 ± 12 | 124 ± 18 | 184 ± 34* | 173 ± 37 | 179 ± 35 | 176 ± 35 | |
AVP-Dobu | 107 ± 9 | 125 ± 12 | 191 ± 30* | 163 ± 16 | 132 ± 16 | 133 ± 16 | |
CVP (mmHg) | Control | 5 ± 0 | 7 ± 1 | 7 ± 0 | 6 ± 1 | 6 ± 1 | 6 ± 1 |
AVP | 5 ± 1 | 8 ± 0‡ | 8 ± 1 | 8 ± 1 | 7 ± 1 | 8 ± 1 | |
AVP-Dobu | 6 ± 1 | 7 ± 1 | 9 ± 1 | 8 ± 1 | 6 ± 1 | 6 ± 1 | |
PAOP (mmHg) | Control | 11 ± 1 | 12 ± 1 | 12 ± 1 | 12 ± 1 | 12 ± 1 | 12 ± 1 |
AVP | 9 ± 0 | 13 ± 1‡ | 15 ± 1 | 15 ± 1 | 15 ± 1 | 14 ± 1 | |
AVP-Dobu | 11 ± 1 | 12 ± 2 | 15 ± 2 | 15 ± 1 | 14 ± 1 | 12 ± 1 | |
SVI (ml beat-1 m-2) | Control | 69 ± 3 | 60 ± 3 | 61 ± 3 | 62 ± 3 | 62 ± 3 | 62 ± 2 |
AVP | 61 ± 3 | 62 ± 4 | 48 ± 5 | 48 ± 6 | 47 ± 3 | 47 ± 3 | |
AVP-Dobu | 70 ± 3 | 63 ± 4 | 49 ± 5 | 59 ± 6 | 63 ± 5† | 64 ± 5†† | |
LVSWI (g m-1 m2) | Control | 79 ± 5 | 57 ± 3‡ | 59 ± 3 | 61 ± 3 | 64 ± 3 | 60 ± 2 |
AVP | 75 ± 3 | 57 ± 4‡ | 62 ± 11 | 62 ± 11 | 68 ± 12 | 70 ± 12 | |
AVP-Dobu | 76 ± 4 | 56 ± 5‡‡ | 59 ± 6 | 80 ± 9 | 95 ± 7**††§ | 94 ± 8**†§ | |
RVSWI (g m-1 m2) | Control | 12 ± 1 | 15 ± 1 | 16 ± 1 | 17 ± 1 | 17 ± 1 | 16 ± 1 |
AVP | 12 ± 1 | 16 ± 1 | 12 ± 2* | 11 ± 1* | 13 ± 1 | 13 ± 1 | |
AVP-Dobu | 13 ± 0 | 15 ± 2 | 11 ± 2** | 14 ± 2 | 16 ± 2 | 17 ± 2 |