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Table 2 Demographics and asymmetrical dimethyl arginine (ADMA) levels by group

From: Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study

Parameter

Survivors

Non-survivors

p

Total patients

33 (70)

14 (30)

 

Male sex

17 (52)

9 (64)

ns

SOFA score, day 1

7 (4–10)

9 (8.75–12.5)

0.02

SOFA score, day 7

4 (2.75–7.25)

10.5 (8.5–11.75)

0.006

SAPS2 score

39 (30.5–51.5)

47.5 (39.5–60.75)

ns

Lactate, day 1

2.1 (1.5–5)

3.6 (2.25–5.75)

ns

Lactate, day 7

1.5 (1–1.9)

2 (1.1–4)

ns

Vasoactive agents, day 1

18 (55)

13 (93)

0.01

Vasoactive agents, day 7

5 (15)

5 (63)

0.005

ADMA, day 1

0.88 (0.52–1.09)

0.91 (0.64–1.23)

ns

ADMA, day 7

1.05 (0.66–1.21)

1.24 (0.77–1.53)

ns

pH, day 1

7.31 (7.26–7.38)

7.33 (7.27–7.37)

ns

pH, day 7

7.44 (7.40–7.45)

7.32 (7.24–7.40)

0.002

WCC, day 1

18 (10.7–23)

9.1 (2.3–17.8)

ns

WCC, day 7

11.6 (8.6–17.4)

13.9 (8.5–19.3)

ns

Base excess, day 1

-2.9 (-6.45 to 1.75)

-4.1 (-9.3 to 1.75)

ns

Base excess, day 7

2.9 (1.1–5.6)

0.1 (-3 to 1.33)

0.009

IL-6, day 1

277 (107–499)

782 (566–1,060)

0.001

IL-6, day 7

22 (0–651)

130 (68–425)

ns

  1. All values are shown either as absolute counts with percentages in parenthesis or as medians with interquartile ranges in parenthesis. ADMA was measured in μmol/l, lactate in mmol/l, and IL-6 in pg/ml. SOFA, Sequential Organ Failure Assessment score; SAPS, simplified acute physiology score; ADMA, asymmetrical dimethyl arginine; WCC, white cell count; ns, not significant.