Table 1 Hemodynamic data, blood gas data in pressure-controlled ventilation (PCV) pre-lavage, PCV post-lavage, and during lung volume optimization procedure in high-frequency oscillatory ventilation
From: Alternative protocol to initiate high-frequency oscillatory ventilation: an experimental study
| Â | PCV pre-lavage | PCV post-lavage | 45 mbar |
|---|---|---|---|
Heart rate (beats/minute) | 113 (112–124) | 112 (102–125) | 141 (126–167) |
Right atrial pressure (mmHg) | 9 (9–9) | 10 (8–11) | 16 (15–18)** |
Mean pulmonary artery pressure (mmHg) | 25 (20–37) | 34 (30–41) | 41 (35.7–52)** |
Pulmonary occlusion pressure (mmHg) | 10 (7–12) | 13 (11–13) | 24 (23–26)** |
Left ventricular end-diastolic pressure (mmHg) | 3 (1–4) | 3.5 (2–6) | 12 (11–13)** |
Mean arterial pressure (mmHg) | 89.5 (67–106) | 83 (82–85) | 85 (66–89) |
Cardiac output (l/min) | 3.28 (3.1–3.5) | 3.6 (3.1–3.9) | 2.6 (2.3–3.1)** |
Stroke volume (ml) | 31 (27–36) | 32 (31–35) | 19 (18–24)** |
Intrathoracic blood volume (ml) | 598.5 (548–622) | 594 (553–690) | 442 (401–469) |
Extravascular lung water (ml) | 290 (241–311) | 420 (354–463)* | 355 (315–476) |
Systemic vascular resistance (dyn*s/cm5) | 1817 (1277–2508) | 1542 (1450–2074) | 2403 (1524–2585) |
Pulmonary vascular resistance (dyn*s/cm5) | 266 (213–775) | 545 (275–693) | 639 (404–859) |
Mean pulmonary artery pressure–right atrial pressure (mmHg) | 16 (11–28) | 26 (22–30) | 28 (19–34) |
Transpulmonary pressure (mbar) | 4.5 (4–6) | 10 (8–11)* | 36 (32–43)** |
PaO2 (Torr) | 559 (535–658) | 99 (56–128)* | 621 (557–522)** |
PaO2/FiO2 ratio | 559 (535–658) | 99 (56–128)* | 621 (557–522)** |
Oxygenation index | 1.4 (1.2–2) | 16.3 (14.6–21.3)* | 7.2 (6.8–7.2)** |
Oxygen delivery (ml O2/minute) | 408.3 (382.5–427.6) | 373 (297.6–427.9) | 312 (299–466.2) |
Shunt proportion | 9.9 (8.8–11) | 51.8 (49–55)* | 1.03 (0.4–3)** |
PaCO2 (Torr) | 39.6 (32.8–48.4) | 47 (40.7–58.8) | 38.5 (28.3–46.6) |
Oxygen saturation (%) | 99.9 (99.9–99.9) | 92 (89.7–96.5)* | 99.9 (99–100)** |
pH | 7.45 (7.4–7.5) | 7.38 (7.31–7.4) | 7.41 (7.37–7.5) |
Standard bicarbonate (mmol/l) | 28.2 (27.8–30.2) | 28.5 (26.2–30.9) | 25 (23.2–27.5) |
Base excess | 4.8 (2.1–5.9) | 2.25 (1–2.9)* | 0.7 (-0.12 to 4.95) |
Hemoglobin (g/dl) | 7.6 (7.5–8) | 7.8 (7.4–8.3) | 7.9 (7.1–9.7) |
Plateau airway pressure (cmH20) | 21 (10.8–14.4) | 30 (25–35) |  |
Inspiratory tidal volume (ml) | 335 (330–450) | 390 (310–440) |  |
Dynamic lung compliance (ml/mbar) | 12.6 (10.8–14.4) | 7.9 (5.3–9.8)* |  |