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Table 2 Mitochondrial respiration and maximal ATP production in the muscle and the kidney at the end of the experiment

From: Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function

Substrate Group Muscle   Kidney  
   n Median (range) n Median (range)
Glutamate      
   State 3 Endotoxic 8 174 (93–114) 7 93 (56–129)
  Control 9 223 (67–494) 8 116 (49–165)
   State 4 Endotoxic 8 18 (13–42) 7 22 (13–40)
  Control 9 20 (11–49) 8 18 (11–27)
   Maximal ATP production Endotoxic 8 328 (187–940) 7 184 (74–431)
  Control 9 606 (153–1233) 8 221 (133–485)
   Respiratory control ratio Endotoxic 8 8.1 (6.7–11.8) 7 4.0 (2.3–6.3)
  Control 9 8.3 (6.0–14.5) 8 5.4 (3.7–7.1)
Succinate      
   State 3 Endotoxic 8 269 (167–467) 7 194 (129–269)
  Control 9 307 (129–579) 8 230 (107–269)
   State 4 Endotoxic 8 56 (36–82) 7 67 (33–98)
  Control 9 62 (31–129) 8 60 (36–78)
   Maximal ATP production Endotoxic 8 513 (356–944) 7 460 (169–707)
  Control 9 611 (421–1164) 8 469(193–1292)
   Respiratory control ratio Endotoxic 8 4.9 (2.9–7.0) 7 3.3 (2.0–3.9)
  Control 9 4.1 (3.6–8.8) 8 3.6 (3.0–3.9)
Ascorbate/N,N,N',N'-tertamethyl-p-phenyldiamine      
   State 3 Endotoxic 8 271 (189–401) 7 134 (98–191)
  Control 9 316 (156–412) 8 150 (116–401)
   State 4 Endotoxic 8 151 (100–200) 7 91 (49–134)
  Control 9 147 (76–254) 8 99 (62–169)
   Respiratory control ratio Endotoxic 8 1.9 (1.4–2.0) 7 1.6 (1.4–2.7)
  Control 9 1.7 (1.4–2.9) 8 1.8 (1.5–2.8)