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Table 1 Heart rate and mean arterial pressure findings

From: Effects of dopexamine on the intestinal microvascular blood flow and leucocyte activation in a sepsis model in rats

 

Group

Time (hours)

  

0

0.5

1

2

3

4

Heart rate (beats/minute)

CON

335 ± 18

347 ± 20

351 ± 20

349 ± 21

343 ± 19

339 ± 9*

 

LPS

342 ± 11

347 ± 12

365 ± 17

387 ± 11

378 ± 11

390 ± 9

 

DPX

321 ± 9

366 ± 9

399 ± 7§

394 ± 8§

384 ± 15§

394 ± 12§

Mean arterial pressure (mmHg)

CON

120 ± 5

119 ± 8*†

109 ± 7*

107 ± 8

116 ± 3

118 ± 5*

 

LPS

116 ± 3

74 ± 2

87 ± 3

94 ± 4

88 ± 3

89 ± 5

 

DPX

120 ± 6

70 ± 2§

107 ± 7§

102 ± 7§

104 ± 8§

99 ± 9§

  1. CON, control group; DPX, DPX group (endotoxin plus dopexamine); LPS, LPS group (endotoxin infusion only). *P < 0.05 CON versus LPS; P < 0.05 CON versus DPX; P < 0.05 LPS versus LPS at baseline; §P < 0.05 DPX versus DPX at baseline.