Figure 3
From: Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding
Population factor VII (FVII) coagulant activity profile modeled from the study dosing regimen. Dots represent the observed FVII coagulant activities from both frequent and sparse sampling while the solid line is trauma average population profile for multiple dosing. This model shows dosing in an adult hemophilia population superimposed for comparison (see Materials and methods).