Figure 2
From: Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding
Correlation between clearance and red blood cell (RBC) transfusion requirement after first dose of recombinant factor VIIa (rFVIIa). Plot of model-estimated, individual clearance versus measured post-dose RBC requirement (n= 123). R-squared value reflects the fraction of the variation in individual predicted clearance values explained by the model. P value reflects the significance level at which the hypothesis of no effect of RBC transfusion need after rFVIIa dosing on individual clearance was rejected. Dotted lines indicate 95% confidence interval of the regression curve.