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Table 2 Transpulmonary pressures, ventilatory parameters, arterial blood gases, calculated pulmonary shunt, oxygen delivery, heart rate, and cerebral perfusion pressure during a lung recruitment procedure by successive increases of mean airway pressure

From: Effect of a lung recruitment maneuver by high-frequency oscillatory ventilation in experimental acute lung injury on organ blood flow in pigs

 

20 mbar mean airway pressure

25 mbar mean airway pressure

30 mbar mean airway pressure

 

HFOV

PCV

HFOV

PCV

HFOV

PCV

Transpulmonary pressure (mbar)

15 ± 3

15 ± 3

19c ± 2

18a ± 3

22cd ± 2

23ab ± 2

Respiratory rate (minute-1)

300

18 ± 10

300

21 ± 11

300

27ab ± 10

Oscillatory pressure amplitude (mbar)

40 ± 7

NA

41 ± 8

NA

52cd ± 8

NA

Dynamic compliance of the respiratory system (ml/mbar)

NA

18 ± 5

NA

17 ± 4

NA

12ab ± 3

Tidal volume per kg bodyweight (ml/kg)

NA

13 ± 3

NA

12 ± 4

NA

10ab ± 2

PaO2 (kPa)

21 ± 4

19 ± 6

57c ± 10

43a ± 21

69cd ± 7

71ab ± 11

PaCO2 (kPa)

5.3 ± 0.3

5.4 ± 0.3

5.4 ± 0.31

5.3 ± 0.3

5.4 ± 0.3

5.4 ± 0.3

Pulmonary shunt (%)

22 ± 8

23 ± 7

6c ± 3

10 ± 6

3cd ± 1

3a ± 1

Oxygen delivery (ml/minute)

347 ± 64

356 ± 73

341 ± 65

353 ± 50

335 ± 63

338 ± 57

Heart rate (minute-1)

119 ± 16

123 ± 19

121 ± 16

129 ± 19

129b ± 18

134a ± 18

Cerebral perfusion pressure (mmHg)

74 ± 15

80 ± 10

68 ± 10

70 ± 8

62b ± 9

65a ± 13

  1. Data presented as the mean ± standard deviation. HFOV, high-frequency oscillatory ventilation; PCV, pressure-controlled ventilation. Dynamic compliance of the respiratory system = tidal volume/(endinspiratory pressure - positive end-expiratory pressure). aP < 0.05 compared with PCV 20 mbar, bP < 0.05 compared with PCV 25 mbar, cP < 0.05 compared with HFOV 20 mbar, dP < 0.05 compared with HFOV 25 mbar. NA, not applicable.