Figure 5
Creatinine clearance as an index of the glomerular filtration rate. Creatinine clearance measured at baseline (t0), endotoxemia (t1) and resuscitation (t2) in the control (C) group (n = 5), nonresuscitation (NR) group (n = 8), HES130/0.4 resuscitation group (n = 8), HES200/0.5 resuscitation group (n = 8) and Ringer's lactate (RL) resuscitation group (n = 6). As lipopolysaccharide infusion was regularly associated with anuria, no clearance could be calculated for these animals. Data were normalized per gram of left kidney weight. Data presented as mean ± standard error of the mean.