Remifentanil/propofol (n = 40) | Midazolam/fentanyl (n = 39) | P valuea | |
---|---|---|---|
Any adverse event | 23 | 24 | NS |
Any drug-related adverse event | 9 | 2 | <0.05 |
Shivering | 8 | 2 | NS |
Pain | 2 | 0 | NS |
Any serious adverse event | 4 | 6 | NS |
Any drug-related serious adverse event | 0 | 0 | NS |
Most commonly occurring adverse events (≥ 5% of patients) | |||
Shivering | 14 | 6 | NS |
Delirium | 7 | 9 | NS |
Pain | 3 | 0 | NS |
Tachycardia | 2 | 0 | NS |
Neuropathy (nerve injury, e.g., by compression) | 1 | 2 | NS |
Respiratory insufficiency | 0 | 3 | NS |
Hypotension | 3 | 0 | NS |
Haemorrhage | 2 | 2 | NS |