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Table 3 Impact of baseline characteristics on the occurrence of acute kidney injury (multivariate logistic regression analysis)

From: RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis

Characteristic Covariates associated with occurrence of acute kidney injury Covariates associated with occurrence of maximum RIFLE class failure
  Odds ratio (95% confidence interval) P Odds ratio (95% confidence interval) P
Age (per year older) 1.02 (1.02–1.03) < 0.001 1.01 (1.00–1.01) 0.001
Race (reference white)   0.130   0.001
   Black 1.20 (0.96–1.50) 0.111 1.50 (1.21–1.86) < 0.001
   Other 0.73 (0.44–1.23) 0.237 0.78 (0.41–1.38) 0.397
Chronic kidney insufficiency 4.19 (2.48–7.10) < 0.001 8.86 (6.01–13.05) < 0.001
Medical admission (reference surgical) 0.79 (0.69–0.90) < 0.001 0.76 (0.66–0.87) < 0.001
Reason for admission according to organ system (reference cardiovascular disease)   < 0.001   < 0.001
   Trauma 0.64 (0.53–0.79) < 0.001 0.64 (0.52–0.80) < 0.001
   Neurological disease 0.93 (0.78–1.13) 0.481 1.02 (0.85–1.2) 0.830
   Pulmonary disease and infection 1.08 (0.88–1.32) 0.461 1.16 (0.96–1.40) 0.120
   Gastrointestinal disease 0.51 (0.35–0.73) < 0.001 0.51 (0.32–0.66) 0.004
   Malignancy 0.36 (0.27–0.49) < 0.001 0.45 (0.31–0.66) < 0.001
   Other 0.57 (0.47–0.70) < 0.001 0.60 (0.48–0.74) < 0.001
SOFAnonrenal (per point greater) 1.19 (1.16–1.21) < 0.001 1.08 (1.06–1.10) < 0.001
In hospital before ICU admission 1.18 (1.03–1.36) 0.015 1.19 (1.04–1.36) 0.012
  1. SOFAnonrenal, Sequential Organ Failure Assessment score without points for kidney insufficiency; ICU, intensive care unit. The odds ratios were calculated with logistic regression analysis. The goodness of fit of the multivariable regression model was tested by the Hosmer-Lemeshow statistic: P = 0.080 for the model with acute kidney injury as the endpoint, and P = 0.019 for the model with maximum Risk, Injury, Failure, Loss, and End-stage Kidney (RIFLE) class failure as the endpoint.
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