Table 2 Comparison of patients with acquisition of A. baumannii with matched controls
Reference | Site of infection; patients and setting | Cases | Controls | Matching of controls to cases | Colonization or infection | Â | Â | Â | Â | Â | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Mortality | Â | Â | Â | Â | Length of ICU stay (days) | |
| Â | Â | Â | Â | Â | Cases | Controls | p | Attributable mortality (%) | Cases | Controls | p |
[21] | Acquisition of Ab in critically ill patients in ICU; medical and surgical ICU in Spain | 75 patients (48 infected and 27 colonized) with Ab | 75 patients without any Ab isolation | (1) Age (± 6 years); (2) sex; (3) APACHE II; (4) date of admission; (5) primary diagnosis of ICU admission; (6) LOS in the ICU at least as long as that of the case before isolation of Ab; (7) Mechanical ventilation for >24 h | ICU: 37/75 (49%) | ICU: 14/75 (19%) | < 0.001 | 30 (95% CI 23–37) | Mean 30.7, SD 26.9, median 23, IQR 11–37 | Mean 13.8, SD 16.4, median 10, IQR 6–15 | < 0.001 |
[20] | Nosocomial acquisition of MDR Ab; MICU in France | 40 patients (13 infected and 27 colonized) with Ab | 40 patients without any Ab isolation | (1) APACHE II score; (2) LOS in the ICU at least as long as that of the case before isolation of Ab; (3) age; (4) date of admission | Hospital: 20/40 (50%) | Hospital: 10/40 (25%) | 0.046 | 25 | Mean 22.6, SD 9.6, median 19, IQR 5–82 | Mean 12.3, SD 12.9, median 11, IQR 3–35 | < 0.001 |
[16] | Nosocomial outbreak of MDR Ab; ICU in USA | 25 patients (9 infected, 15 colonized) with Ab | 32 patients with cultures negative for Ab | (1) Same ICU; (2) date of admission | Hospital: 13/25 (52%) | Hospital: 8/32 (25%) | 0.036 | 27 | Mean 19.6, median 18 | Mean 6.1, median 4.5 | < 0.05 |
[17] | Colonization or infection due to (89% MDR) Ab; trauma centre in USA. Most patients were in medical, surgical, and burns ICUs | 102 patients (33 infected, 69 colonized) with Ab | 102 controls without Ab | (1) Primary diagnosis (computerized codes); (2) same period | Hospital: 35/102 (34%) | Hospital: 18/102 (18%) | 0.007 | 16 | Mean 27.35, SD 28.21 | Mean 5.53, SD 15.87 | < 0.001 |
[19] | Colonization or infection due to Ab; university hospital in France. 52% of the patients were hospitalized in an ICU | 121 patients (infected or colonized) with Ab | 121 patients with the same specimen as cases found negative for Ab | (1) Same unit; (2) same period; (3) same type of specimen | NR | NR | NR | NR | Mean 29, SD 20 | Mean 13, SD 10 | NR |