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Table 2 Comparison of patients with acquisition of A. baumannii with matched controls

From: Attributable mortality of Acinetobacter baumannii infections in critically ill patients: a systematic review of matched cohort and case-control studies

Reference Site of infection; patients and setting Cases Controls Matching of controls to cases Colonization or infection      
      Mortality      Length of ICU stay (days)
      Cases Controls p Attributable mortality (%) Cases Controls p
[21] Acquisition of Ab in critically ill patients in ICU; medical and surgical ICU in Spain 75 patients (48 infected and 27 colonized) with Ab 75 patients without any Ab isolation (1) Age (± 6 years); (2) sex; (3) APACHE II; (4) date of admission; (5) primary diagnosis of ICU admission; (6) LOS in the ICU at least as long as that of the case before isolation of Ab; (7) Mechanical ventilation for >24 h ICU: 37/75 (49%) ICU: 14/75 (19%) < 0.001 30 (95% CI 23–37) Mean 30.7, SD 26.9, median 23, IQR 11–37 Mean 13.8, SD 16.4, median 10, IQR 6–15 < 0.001
[20] Nosocomial acquisition of MDR Ab; MICU in France 40 patients (13 infected and 27 colonized) with Ab 40 patients without any Ab isolation (1) APACHE II score; (2) LOS in the ICU at least as long as that of the case before isolation of Ab; (3) age; (4) date of admission Hospital: 20/40 (50%) Hospital: 10/40 (25%) 0.046 25 Mean 22.6, SD 9.6, median 19, IQR 5–82 Mean 12.3, SD 12.9, median 11, IQR 3–35 < 0.001
[16] Nosocomial outbreak of MDR Ab; ICU in USA 25 patients (9 infected, 15 colonized) with Ab 32 patients with cultures negative for Ab (1) Same ICU; (2) date of admission Hospital: 13/25 (52%) Hospital: 8/32 (25%) 0.036 27 Mean 19.6, median 18 Mean 6.1, median 4.5 < 0.05
[17] Colonization or infection due to (89% MDR) Ab; trauma centre in USA. Most patients were in medical, surgical, and burns ICUs 102 patients (33 infected, 69 colonized) with Ab 102 controls without Ab (1) Primary diagnosis (computerized codes); (2) same period Hospital: 35/102 (34%) Hospital: 18/102 (18%) 0.007 16 Mean 27.35, SD 28.21 Mean 5.53, SD 15.87 < 0.001
[19] Colonization or infection due to Ab; university hospital in France. 52% of the patients were hospitalized in an ICU 121 patients (infected or colonized) with Ab 121 patients with the same specimen as cases found negative for Ab (1) Same unit; (2) same period; (3) same type of specimen NR NR NR NR Mean 29, SD 20 Mean 13, SD 10 NR
  1. Acquisition of A. baumannii is defined as patients colonized or infected with the organism; matched controls were those without acquisition of the organism. Ab, Acinetobacter baumannii; APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidence interval; ICU, intensive care unit; IQR, interquartile range; LOS, length of stay; MDR, multidrug resistant; NR, not reported.
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