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Table 2 Correlation of time-related cytokine production with organ dysfunctions measured within 24 hours after surgery

From: Circulating inflammatory mediators and organ dysfunction after cardiovascular surgery with cardiopulmonary bypass: a prospective observational study

Organ dysfunction

Inflammatory markers

p

 

AI

After CPB

 
  

3 hours

6 hours

10 hours

 

Circulationa

 

MIF

  

0.017

  

IL-10

  

0.011

    

IL-6

0.05

Hematologicalb

 

MCP-1

  

0.014

   

MCP-1

 

0.026

    

MCP-1

0.002

Pulmonaryc

MIF

   

0.041

  

MIF

  

<0.001

  

IL-10

  

0.032

  1. aDefined as noreprinephrine > 1.0 μg/kg per minute; bdefined as platelets < 133,000/mm3; cdefined as a ratio of partial arterial oxygen tension to fraction of inspired oxygen of less than 196. AI, anesthesia induction; CPB, cardiopulmonary bypass; MCP, monocyte chemoattractant protein; MIF, macrophage migration inhibitory factor.
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Critical Care

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