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Table 2 Terlipressin (TP) treatment and outcome

From: Rescue treatment with terlipressin in children with refractory septic shock: a clinical study

Patient

Time from PICU admission to TP therapy (hours)

Time of maintenance of TP therapy (hours)

Adverse effectsa

PICU length of stay (days)

Survival of episode

Cause of death

Sequela

1

40

48

No

49

Yes

 

Minor amputation (one right hand finger)

2

4

32

Ischemia (limited to toes)

7

Yes

 

No

3

12

65

No

51

No

Refractory shock

 

4

6

3

Severe limbs and cutaneous ischemia, hyperkalemia

6

No

Ventricular fibrillation

 

5

24

24

Limbs and cutaneous ischemia

22

Yes

 

Major amputation: lower limbs (below knees) and both hands

6

72

102

No

49

Yes

 

Minor amputation (one hand finger)

7

26

8

Severe limbs ischemia, cutaneous ischemia, hyperbilirubinemia

14

No

Withdraw of therapy

 

8

48

20

Rabdomyolisis?

22

Yes

 

No

9

4

5

Oliguria

9

Yes

 

Partial anopsy, dismetry

10

32

96

Cutaneous and intestinal ischemia

6

No

Withdraw of therapy

 

11

168

52

Limb and cutaneous ischemia, oliguria

8

No

Multiorgan failure

 

12

14

7

No

1

No

Arrhythmia

 

13

60

8

No

3

No

Ventricular fibrillation

 

14

20

20

No

1

No

Refractory shock

 

15

5

18

Limbs ischemia, rabdomyolisis

2

No

Refractory shock

 

16

48

72

Limbs and cutaneous ischemia

14

Yes

  
  1. PICU, pediatric intensive care unit. aBased in the opinion of the responsible physician