Skip to main content
Download PDF

Volume 1 Supplement 1

17th International Symposium on Intensive Care and Emergency Medicine

  • Meeting abstract
  • Published:

The cardiopulmonary bypass supported high-risk PTCA (CPB-PTCA): a useful model for the study of CPB-dependent systemic inflammatory response syndrome (SIRS)?

Critical Care volume 1, Article number: P033 (1997) Cite this article

The mechanisms underlying myocardial depression following open heart surgery with extracorporeal circulation is still a matter of debate. One important trigger mechanism responsible for myocardial depression seems to be related to the release of cytokines during the systemic inflammatory response. Aim of the present study was to investigate whether CPB supported PTCA might be a useful model for the differentiation of surgery-dependent and CPB-SIRS-induced myocardial depression.

Methods

PTCA supported angioplasty with CPB; transesophageal echocardiography; wall motion score (WMS); plasma levels of cytokines and parameters as shown in the table. Seven patients, mean age 61.3 years, ejection fraction, 17–64%: five patients with three-vessel-CAD; two patients with two-vessel-CAD: four patients with CABG. (I) Before CPB: (II) beginning CPB: (III) immediately before PTCA; (IV) end CPB.

Results

See table.

Summary

CPB-PTCA helps to discriminate between surgery-induced and CBP-dependent systemic inflammatory response syndrome.

Table 1
Full size table
Table 2
Full size table

Author information

Authors and Affiliations

  1. Lehrstuhl für Kardiologische Intensiemedisin, Germany

    R Prondzinsky, R Witthaut & R Werdan

  2. Klinik für Innere Medizin III, Germany

    I Stabenow & W Teichmann

  3. Klinik für Anästhesiologie and Operative Intensiemedisin, Germany

    D Lehmann

  4. Klinik für Hers- und Thorax-chirurgie, Klinikum Kröllwits, Marin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str-40, 06097, Halle, Germany

    F Redling & HR Zerkowski

  5. Institut für Klinische Chemie, Klinikum Groβhadern, Ludwig-Maximilians-Universität München, Marchionistr 15, 81377, Munchen, Germany

    P Fraunberger, AK Walli & D Seidel

Authors
  1. R Prondzinsky
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R Witthaut
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I Stabenow
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D Lehmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F Redling
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. P Fraunberger
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. AK Walli
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. D Seidel
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. HR Zerkowski
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. W Teichmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. R Werdan
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Prondzinsky, R., Witthaut, R., Stabenow, I. et al. The cardiopulmonary bypass supported high-risk PTCA (CPB-PTCA): a useful model for the study of CPB-dependent systemic inflammatory response syndrome (SIRS)?. Crit Care 1 (Suppl 1), P033 (1997). https://doi.org/10.1186/cc39

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/cc39

Keywords

Critical Care

ISSN: 1364-8535