Table 4 Immunmodulatory parameters at the time of hospital-acquired pneumonia diagnosis
Immunmodulatory parameters (n = 76) | Pneumonia without subsequent septic shock (n = 47)a | Pneumonia with subsequent septic shock (n = 29)a | p value |
|---|---|---|---|
TNF-α (pg/ml) | 7.0 (6.0–9.0) | 12.0 (8.0–15.0) | ≤ 0.01 |
IL-1β (pg/ml) | 1.2 (1.0–1.4) | 1.85 (1.3–2.0) | ≤ 0.01 |
IL-6 (pg/ml) | 64.0 (29.0–155.0) | 367.0 (166.5–678.1) | ≤ 0.01 |
IL-8 (pg/ml) | 73.0 (52.0–103.0) | 187.0 (106.1–410.0) | ≤ 0.01 |
IL-10 (pg/ml) | 15.0 (8.0–24.0) | 47.0 (21.7–144.0) | ≤ 0.01 |
E-selectin (ng/ml) | 34.0 (24.0–56.0) | 71.0 (42.5–115.0) | ≤ 0.01 |