Table 1 Concentrations of measured anions in plasma (μEq l^-1)

From: Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis

Acid	Patient group
	Diabetic ketoacidosis			Lactic acidosis			Unknown origin			Normal anion gap			Controls
	Mean	SD	p	Mean	SD	p	Mean	SD	p	Mean	SD	p	Mean	SD
Citrate	454.02	194.11	ns	1,453.13	513.95	<0.01	335.63	69.82	ns^a	239.1	105.1	ns	448.55	119.80
Isocitrate	421.93	352.56	0.02	704.6	347.6	<0.01	949.16	883.22	<0.01^a	84.48	69.6	ns^a	60.97	31.31
α-Ketoglutarate	413.41	158.48	<0.01^a	547.72	344.98	<0.01^a	651.51	203.06	<0.01^a	72.97	67.34	ns^a	79.17	106.74
Succinate	181.1	173.24	ns	358.27	112.49	<0.01^a	340.04	128.74	0.02^a	125.89	73.57	ns^a	90.29	49.97
Malate	229.81	181.87	<0.01^a	593.65	265.88	<0.01	485.16	189.67	<0.01^a	95.07	117.59	ns	59.82	32.94
d-Lactate	157.34	67.85	<0.01	397.69	511.15	<0.01^a	176.49	135.21	<0.01	69.27	55.39	<0.01	35.63	18.42

For each group, statistical analysis is presented relative to control value. ^aMann-Whitney non-parametric test. ns, not significant; SD, standard deviation.

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