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Table 1 Case mix for admissions with chronic obstructive pulmonary disease by subgroup

From: Case mix and outcomes for admissions to UK adult, general critical care units with chronic obstructive pulmonary disease: a secondary analysis of the ICNARC Case Mix Programme Database

 

All (n = 3752)

I. Pneumonia (n = 775)

II. Right VF (n = 147)

III. Left VF (n = 142)

Age (years; median [IQR])

67.8 (60.5–73.6)

68.7 (61.4–74.0)

68.8 (61.7–74.0)

71.9 (67.2–75.1)

Sex (n [%] male)

1942 (51.8)

401 (51.7)

83 (56.5)

81 (57.0)

Past medical history (n [%])

    

   Respiratory impairment

    

Severe respiratory disease

1236 (35.0)

232 (31.6)

57 (42.2)

33 (25.2)

Home ventilation

70 (2.0)

6 (0.8)

6 (4.4)

2 (1.5)

   Steroid treatment

305 (8.6)

61 (8.3)

7 (5.2)

8 (6.1)

   Comorbidity:

    

Liver disease

6 (0.2)

3 (0.4)

0 (0.0)

0 (0.0)

Cardiovascular disease

79 (2.2)

11 (1.5)

8 (5.9)

10 (7.6)

Chronic renal failure

11 (0.3)

1 (0.1)

0 (0.0)

0 (0.0)

Immunosuppression

27 (0.4)

3 (0.1)

1 (0.7)

1 (0.8)

Metastatic cancer

6 (0.5)

1 (0.4)

0 (0.0)

0 (0.0)

   Hospital stay prior to unit admission (days; median [IQR])

1 (0–3)

1 (0–3)

1 (0–2)

0 (0–2)

   CPR prior to admission (n [%])a

308 (8.3)

45 (5.8)

20 (13.8)

12 (8.5)

   Intubation status (n [%])b

    

Definitely intubated

2774 (73.9)

605 (78.1)

104 (13.8)

103 (72.5)

Probably intubated

278 (7.4)

56 (7.2)

13 (8.8)

9 (6.3)

Not intubated

700 (18.7)

114 (14.7)

30 (20.4)

30 (21.2)

Physiologyb

    

   Lowest pH (median [IQR])

7.26 (7.18–7.33)

7.26 (7.18–7.33)

7.25 (7.19–7.33)

7.24 (7.15–7.32)

   PaCO2 (kPa; median [IQR])c

8.7 (6.9–10.7)

8.6 (6.9–10.6)

9.1 (7.2–11.7)

7.6 (6.4–10.4)

   PaO2/FiO2 gradient (kPa; median [IQR])d

22.9 (17.2–29.6)

21.2 (15.3–27.8)

20.9 (17.2–26.2)

23.3 (15.9–29.3)

   Lowest serum albumin (g/l; median [IQR])

28 (23–33)

26 (21–31)

28 (25–32)

30 (25–34)

   APACHE II

    

APS (mean [SD])

13.4 (5.6)

14.3 (5.5)

13.5 (5.1)

14.6 (6.2)

APS (median [IQR])

12 (10–16)

13 (10–17)

13 (10–17)

14 (10–18)

Score (mean [SD])

19.4 (6.4)

20.3 (6.3)

19.9 (5.8)

20.7 (6.8)

Score (median [IQR])

19 (15–23)

19 (16–23)

19 (16–24)

20 (16–24)

   APACHE III

    

APS (mean [SD])

52.9 (21.5)

55.9 (21.6)

53.4 (20.0)

56.8 (21.5)

APS (median [IQR])

50 (39–64)

52 (42–68)

53 (41–66)

55 (42–68)

Score (mean [SD])

65.9 (23.0)

69.3 (23.0)

66.6 (21.8)

71.6 (22.9)

Score (median [IQR])

63 (50–78)

66 (54–83)

66 (52–80)

69.5 (55–84)

   Organ system failures (n [%])

    

0

457 (12.2)

85 (11.0)

19 (12.9)

15 (10.6)

1 Respiratory

1767 (45.2)

362 (45.0)

56 (37.4)

55 (33.8)

1 Other

214 (4.4)

60 (9.3)

5 (4.1)

9 (8.5)

2

1036 (27.6)

215 (27.7)

50 (34.0)

50 (35.2)

3 or more

309 (8.2)

54 (7.0)

17 (11.6)

17 (12.0)

  1. aDuring 24 hours before unit admission. bDuring first 24 hours following unit admission. cTaken from ABG with lowest pH. d Taken from ABG with lowest PaO2. ABG, arterial blood gas; APACHE, Acute Physiology and Chronic Health Evaluation; APS, Acute Physiology Score; CPR, cardiopulmonary resuscitation; FiO2, fractional inspired oxygen; IQR, interquartile range; PaO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension; SD, standard deviation; VF, ventricular failure.