Volume 1 Supplement 1

17th International Symposium on Intensive Care and Emergency Medicine

Open Access

Multi-organ-failure (MOF) with and without sepsis: differences in incidence and pattern of detected arrhythmias

  • R Prondzinsky1,
  • N Stache1,
  • R Witthaut1,
  • M Winkler2,
  • P Fraunberger3,
  • AK Walli3,
  • D Seidel3 and
  • K Werdan 1
Critical Care19971(Suppl 1):P030

https://doi.org/10.1186/cc36

Published: 1 March 1997

Background and objectives

Aim of the present study was to prospectively examine if there is a difference in spectrum of arrhythmias occurring in patients with Elebute and Stoner score (≥ 12, group 1) - quantified sepsis in relation to MOF patients without sepsis (group 2). Group 3: ICU patients without severe MOF and without sepsis.

Methods

24 h Holter-monitoring, APACHE-II and sepsis-scoring; plasma levels of cytokines.

Results

See table.

Conclusions

In our pilot study, no significant higher incidence of ventricular arrhythmias has been seen in MOF patients with and without sepsis.

Table

 

Group 1 (n = 25)

Group 2 (n = 15)

Group 2 (n = 7)

Elebute score

17.8 ± 6.0

7.1 ± 2.8*

0.4 ± 0.5*

APACHE II score

32.4 ± 6.8

26.1 ± 7.3*

10.7 ± 13.7*

TNF-α (pg/ml)

88 ± 72

31 ± 27

29 ± 16

s-SVES/24 h**

1 736 ± 3717

1966 ± 4982

744 ± 1451

SVT/24 h

37.7 ± 107.2

279 ± 906

86.7 ± 175

s-VES/24 h**

652 ± 1672

790 ± 2394

1143 ± 2357

v-Couplet/24 h

49 ± 485

90.6 ± 308

81.7 ± 194

VT/24 h

184 ± 709

9.5 ± 28.3

41.6 ± 105

*P < 0.05, data are presented as mean ± SD> There was no correlation between SVES/VES and iv therapy with norepinehrine, epinephrine, dopamine and dobutamine, respectively. n = 12, n = 13, §n = 6, **s = single (SVES/VES).

Authors’ Affiliations

(1)
Lehrstuhl für Kardiologische Intensivmedizin
(2)
Klinik für Innere Medizin I, Klinikum Kröllwitz, Martin-Luther-Unversität Halle-Wittenberg
(3)
Institut für Klinische Chemie, Klinikum Groβhadern, Ludwig-Maximilians-Universität München

Copyright

© Current Science Ltd 1997

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