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Table 3 Effects of pulse high-volume haemofiltration on haemodynamic variables

From: Pulse high-volume haemofiltration for treatment of severe sepsis: effects on hemodynamics and survival

Variables Pre-PHVHF Mid-PHVHF End-PHVHF 6 hours after PHVHF 12 hours after PHVHF P
Noradrenaline Dose (μg/min) 48 (0–114) 40 (0–97)* 40 (0–93) 40 (0–69)* 33 (0–67)** 0.001
SBP (mmHg) 124.32 ± 25.63 126.64 ± 22.10 133.00 ± 24.55 133.06 ± 23.88 133.16 ± 26.15 0.04
MAP (mmHg) 82.16 ± 18.31 85.02 ± 18.82 86.88 ± 17.56 87.76 ± 20.65 87.26 ± 22.05 NS
CI (l/min per m2) 3.4 ± 1.1 3.4 ± 1.2 3.5 ± 1.0 3.5 ± 1.1 3.5 ± 1.2 NS
HR (beats/min) 97.28 ± 25.53 99.62 ± 22.94 100.06 ± 21.79 99.94 ± 20.71 95.62 ± 20.66 0.04
Temperature (°C) 36.7 ± 1.0 36.8 ± 0.8 36.8 ± 0.8 36.9 ± 0.8 36.7 ± 0.9 NS
PaO2/FiO2 230.9 ± 109.1 232.8 ± 104.4 243.0 ± 105.6 230.2 ± 109.9 234.6 ± 106.4 NS
  1. Normally distributed values are reported as mean ± standard deviation, and the statistical test used was analysis of variance for repeated measurements. Non-normally distributed values are reported as median (25th to 75th percentile), and P value was determined using Friedman's two-way analysis of varience with post-hoc Wilcoxon signed rank test. *P < 0.05, **P < 0.01 versus baseline. HR, heart rate; CI, cardiac index; MAP, mean arterial pressure; PaO2/FiO2, arterial oxygen tension/fractional inspired oxygen; PHVHF, pulse high-volume haemofiltration; SBP, systolic blood pressure.