|
Variables
|
Pre-PHVHF
|
Mid-PHVHF
|
End-PHVHF
|
6 hours after PHVHF
|
12 hours after PHVHF
|
P
|
|---|
|
Noradrenaline Dose (μg/min)
|
48 (0–114)
|
40 (0–97)*
|
40 (0–93)
|
40 (0–69)*
|
33 (0–67)**
|
0.001
|
|
SBP (mmHg)
|
124.32 ± 25.63
|
126.64 ± 22.10
|
133.00 ± 24.55
|
133.06 ± 23.88
|
133.16 ± 26.15
|
0.04
|
|
MAP (mmHg)
|
82.16 ± 18.31
|
85.02 ± 18.82
|
86.88 ± 17.56
|
87.76 ± 20.65
|
87.26 ± 22.05
|
NS
|
|
CI (l/min per m2)
|
3.4 ± 1.1
|
3.4 ± 1.2
|
3.5 ± 1.0
|
3.5 ± 1.1
|
3.5 ± 1.2
|
NS
|
|
HR (beats/min)
|
97.28 ± 25.53
|
99.62 ± 22.94
|
100.06 ± 21.79
|
99.94 ± 20.71
|
95.62 ± 20.66
|
0.04
|
|
Temperature (°C)
|
36.7 ± 1.0
|
36.8 ± 0.8
|
36.8 ± 0.8
|
36.9 ± 0.8
|
36.7 ± 0.9
|
NS
|
|
PaO2/FiO2
|
230.9 ± 109.1
|
232.8 ± 104.4
|
243.0 ± 105.6
|
230.2 ± 109.9
|
234.6 ± 106.4
|
NS
|
- Normally distributed values are reported as mean ± standard deviation, and the statistical test used was analysis of variance for repeated measurements. Non-normally distributed values are reported as median (25th to 75th percentile), and P value was determined using Friedman's two-way analysis of varience with post-hoc Wilcoxon signed rank test. *P < 0.05, **P < 0.01 versus baseline. HR, heart rate; CI, cardiac index; MAP, mean arterial pressure; PaO2/FiO2, arterial oxygen tension/fractional inspired oxygen; PHVHF, pulse high-volume haemofiltration; SBP, systolic blood pressure.
