Skip to main content

Table 4 Characteristics of treatment and outcome in 20 patients with Aspergillus spp. infection

From: Isolation of Aspergillus spp. from the respiratory tract in critically ill patients: risk factors, clinical presentation and outcome

Case APACHE II score at start of treatment Antifungal agent Total doses (mg) Days of treatment Microbiological eradication Clinical cure Outcome
1 18 Liposomal amphotericin B 2450 21 Yes Yes Alive
2 29 Itraconazole - 5 ? No Death in the ICU
3 17 Liposomal amphotericin B 3100 21 ? Yes Alive
4 17 Liposomal amphotericin B 2650 17 Yes Yes Death in the hospital
5 20 Liposomal amphotericin B 600 4 ? No Death in the ICU
6 16 Amphotericin B deoxycholate 450 10 No No Alive
7 ? Amphotericin B deoxycholate 1050 21 Yes Yes Alive
8 23 Amphotericin B deoxycholate 180 5 ? No Death in the ICU
9 20 Amphotericin B deoxycholate 1050 7 No No Death in the ICU
10 19 Amphotericin B lipid complex 2300 9 No No Death in the ICU
11 22 Liposomal amphotericin B 3180 21 ? No Death in the ICU
12 22 Liposomal amphotericin B 3300 15 Yes Yes Death in the ICU
13 11 Amphotericin B deoxycholate/liposomal amphotericin B 1200/1200 12/4 No No Death in the ICU
14 32 Liposomal amphotericin B 4000 16 Yes Yes Death in the ICU
15 45 Amphotericin B lipid complex 2400 8 ? Yes Alive
16 16 Amphotericin B deoxycholate/amphotericin B lipid complex 350/300 6/2 No No Death in the ICU
17 25 Amphotericin B lipid complex/liposomal amphotericin B 3600/6300 14/21 No/Yes No/Yes Death in the ICU
18 ? Amphotericin B deoxycholate 420 7 ? No Death in the ICU
19 34 Amphotericin B deoxycholate 450 7 ? No Death in the ICU
20 23 Liposomal amphotericin B 2200 11 Yes Yes Alive
  1. APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit.