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Table 1 Histopathologic scores in the three groups

From: The effect of activated protein C on experimental acute necrotizing pancreatitis

Feature

Group I (sham)

Group II (control)

Group III (treatment)

P (group II versus group III)

Edema

0.67 ± 0.13

3.09 ± 0.16

2.38 ± 0.14

<0.007a

Acinar necrosis

0.07 ± 0.06

1.82 ± 0.12

1.08 ± 0.08

<0.001a

Inflammatory infiltrate

0.73 ± 0.12

2.91 ± 0.16

2.00 ± 0.16

<0.002a

Hemorrhage

0.27 ± 0.12

2.45 ± 0.16

2.08 ± 0.18

NSa

Fat necrosis

0.13 ± 0.09

1.82 ± 0.12

1.31 ± 0.13

<0.02a

Perivascular Inflammation

0.13 ± 0.09

1.91 ± 0.09

1.38 ± 0.14

<0.02a

Histopathologic score

2.00 ± 0.28

14.00 ± 0.52

10.31 ± 0.47

<0.001b

  1. Values are expressed as mean score ± standard error of the mean. aBy Mann–Whitney U test.
  2. bBy Tukey HSD. NS, not significant.