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Table 2 Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by lung water content

From: Extravascular lung water in patients with severe sepsis: a prospective cohort study

 

Non-ARDS

ARDS

 

Low EVLW (n = 6)

High EVLW (n = 8)

P

Low EVLW (n = 4)

High EVLW (n = 11)

P

EVLW (ml/kg)

5.0 (4.8–8.1)

7.7 (5.0–8.7)

NS

9.0 (8.0–9.8)

16.0 (13.0–20.3)

0.07

Source (n [% pulmonary])

2/6 (33%)

3/8 (38%)

NS

3/4 (75%)

8/11 (73%)

NS

APACHE II score

27.8 ± 2.3

27.6 ± 11.6

NS

18.5 ± 3.3

25.9 ± 6.3

0.05

PaO2/FiO2 index (mmHg)

424.0 ± 51.7

244.3 ± 133.9

0.02

91.5 ± 24.6

144.9 ± 89.9

NS

LIS

0.8 ± 0.2

0.9 ± 0.9

NS

2.6 ± 1.7

2.7 ± 1.1

NS

CXR score

0.5 (0–1)

1 (0–2)

NS

3 (2–4)

4 (3–4)

NS

GEDV index (ml/m2)

750.5 ± 133.6

691.3 ± 108.1

NS

581.5 ± 131.4

671.8 ± 200.0

NS

Fluid balance (prior 24 hours; ml)

5256 ± 4918

4664 ± 1591

NS

2373 ± 776

2545 ± 2959

NS

Chronic alcohol abuse (n [%])

4/6 (67%)

4/8 (50%)

NS

0/4 (0%)

5/11 (45%)

0.09

28-Day mortality (n [%])

1/6 (17%)

4/8 (50%)

0.20

0/4 (0%)

7/11 (64%)

0.03

  1. Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome.