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Table 2 Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by lung water content

From: Extravascular lung water in patients with severe sepsis: a prospective cohort study

  Non-ARDS ARDS
  Low EVLW (n = 6) High EVLW (n = 8) P Low EVLW (n = 4) High EVLW (n = 11) P
EVLW (ml/kg) 5.0 (4.8–8.1) 7.7 (5.0–8.7) NS 9.0 (8.0–9.8) 16.0 (13.0–20.3) 0.07
Source (n [% pulmonary]) 2/6 (33%) 3/8 (38%) NS 3/4 (75%) 8/11 (73%) NS
APACHE II score 27.8 ± 2.3 27.6 ± 11.6 NS 18.5 ± 3.3 25.9 ± 6.3 0.05
PaO2/FiO2 index (mmHg) 424.0 ± 51.7 244.3 ± 133.9 0.02 91.5 ± 24.6 144.9 ± 89.9 NS
LIS 0.8 ± 0.2 0.9 ± 0.9 NS 2.6 ± 1.7 2.7 ± 1.1 NS
CXR score 0.5 (0–1) 1 (0–2) NS 3 (2–4) 4 (3–4) NS
GEDV index (ml/m2) 750.5 ± 133.6 691.3 ± 108.1 NS 581.5 ± 131.4 671.8 ± 200.0 NS
Fluid balance (prior 24 hours; ml) 5256 ± 4918 4664 ± 1591 NS 2373 ± 776 2545 ± 2959 NS
Chronic alcohol abuse (n [%]) 4/6 (67%) 4/8 (50%) NS 0/4 (0%) 5/11 (45%) 0.09
28-Day mortality (n [%]) 1/6 (17%) 4/8 (50%) 0.20 0/4 (0%) 7/11 (64%) 0.03
  1. Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome.