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Table 3 Systemic and intestinal CO2-derived parameters in sham, normal and increased blood flow groups

From: Increased blood flow prevents intramucosal acidosis in sheep endotoxemia: a controlled study

Parameter Group Basal Endotoxemia
    30 min 60 min 90 min 120 min
Mixed venous – arterial PCO2 (mmHg) Sham 6 ± 2 6 ± 2 6 ± 2 6 ± 2 5 ± 2
  Normal 7 ± 2 8 ± 2 7 ± 2 8 ± 3 8 ± 3†
  Increased 6 ± 2 6 ± 3 7 ± 5 7 ± 4 4 ± 1‡
Mesenteric venous – arterial PCO2 (mmHg) Sham 6 ± 2 5 ± 2 5 ± 2 6 ± 2 5 ± 2
  Normal 7 ± 2 8 ± 2 8 ± 3 10 ± 4 10 ± 2*†
  Increased 8 ± 3 6 ± 2 8 ± 4 8 ± 3 6 ± 1*‡
Intramucosal – arterial PCO2 (mmHg) Sham 4 ± 4 5 ± 8 5 ± 8 5 ± 8 6 ± 9
  Normal 7 ± 4 6 ± 5 12 ± 5 15 ± 6*‡ 19 ± 4*‡
  Increased 5 ± 7 2 ± 9 7 ± 7 12 ± 8 9 ± 6†
Systemic VCO2 (ml/min per kg) Sham 5.2 ± 1.9 4.5 ± 1.2 4.0 ± 1.5 4.7 ± 1.2 4.6 ± 1.8
  Normal 6.0 ± 2.4 4.9 ± 1.4 4.9 ± 1.7 5.0 ± 1.3 5.0 ± 1.7
  Increased 6.5 ± 2.5 4.8 ± 2.4 6.1 ± 2.8 5.8 ± 2.3 5.8 ± 4.7
Intestinal VCO2 (ml/min per kg) Sham 36.7 ± 10.9 38.1 ± 11.3 34.0 ± 8.8 43.2 ± 10.6 36.7 ± 5.6
  Normal 37.7 ± 10.9 35.3 ± 11.6 37.2 ± 13.7 41.8 ± 20.3 36.7 ± 16.2
  Increased 36.5 ± 21.8 35.3 ± 14.6 27.4 ± 9.4 35.8 ± 12.9 34.0 ± 7.4
Mixed venous blood capacity for transporting CO2 (ml/100 ml per mmHg) Sham 0.67 ± 0.12 0.59 ± 0.40 0.51 ± 0.11 0.61 ± 0.21 0.61 ± 0.13
  Normal 0.62 ± 0.12 0.49 ± 0.12* 0.55 ± 0.04* 0.47 ± 0.09* 0.44 ± 0.09*†
  Increased 0.67 ± 0.24 0.38 ± 0.27* 0.42 ± 0.24* 0.45 ± 0.19* 0.48 ± 0.12*†
Mesenteric venous blood capacity for transporting CO2 (ml/100 ml per mmHg) Sham 1.14 ± 0.24 1.15 ± 0.32 1.22 ± 0.29 1.37 ± 0.22 1.28 ± 0.08
  Normal 1.04 ± 0.22 0.99 ± 0.38 0.86 ± 0.24† 0.78 ± 0.33*† 0.76 ± 0.24*†
  Increased 1.17 ± 0.45 0.85 ± 0.29 0.66 ± 0.27† 0.81 ± 0.19† 0.69 ± 0.18*†
  1. * P < 0.05 versus basal. † P < 0.05 versus sham. ‡ P < 0.05 versus normal. Sham, sham group; normal, normal blood flow group; increased, increased blood flow group.