Skip to main content

Table 3 Approximate sensitivity and specificity of antineutrophil cytoplasmic antibody in detecting primary vasculitides

From: Clinical review: Vasculitis on the intensive care unit – part 1: diagnosis

 

Sensitivity (%)

Specificity (%)

WG

  

   cANCA

64

95

   PR-3

66

87

   PR-3 + ANCA

55

99

MPA

  

   pANCA

58

81

   MPO

58

91

   MPO + ANCA

49

99

WG or MPA

  

   PR-3 + cANCA or MPO + pANCA

67–73

99

  1. cANCA, cytoplasmic antineutrophil cytoplasmic antibody; MPA, microscopic polyangiitis; MPO, myeloperoxidase; pANCA, perinuclear antineutrophil cytoplasmic antibody; PR, proteinase; WG, Wegener's granulomatosis. Data from Hagen and coworkers [22].