Combination of histopathological and electromyographic patterns can help to evaluate functional outcome of critical ill patients with neuromuscular weakness syndromes

Table 2 Electrodiagnostic and histopathological findings in 15 patients with neuromuscular weakness syndromes

Patient	Type^a	Electromyography										Muscular biopsy			Nerve biopsy
		Concentric needle examinatioin						Motor nerve conduction		Sensory nerve conduction		Atrophy	Necrosis	Myosin loss	Axonal degeneration	Demyelination
		FP	LP	Recruitment^b
				0	1	2	3	CV (m/s)	CMAP (mV)	CV (m/s)	CMAP (µV)
1	N	+		+				Peroneal 46/ulnar 68	1/0.1			I/II			+
2	N	+		+				Peroneal 0/median 0	0/0	Sural 0/radial 0	0/0	II	+		+
3	N	+	+			+		Peroneal 33	0.1	Peroneal 41	10	I	+		+
4	N	+	+					Peroneal 26/median 37	1/1	Peroneal 35/median 38	2/1	I/II			+	+
5	N	+		+		+		Peroneal 41	3	Peroneal 33	4	I/II	+		+	+
6	N	+		+			+	Peroneal 40	2	Peroneal 36/radial 48	7/48	I/II	+		+	+
7	NM	+		+				Peroneal 0	0	Peroneal 0	0	I/II	+		+	+
8	NM	+	+					Peroneal 0	0	Peroneal 0	0	I/II	+	+	+
9	NM	+	+			+		Peroneal 38	0.1	Peroneal 35/radial 48	3/8	I/II	+	+	+
10	M	+			+	+	+	Peroneal 36/median 34	0.8/0.8	Peroneal 52/radial 56	7/16	II	+	+	No	No
11	M			+				Peroneal 42	1.6	Peroneal 58	12	II		+	No	No
12	M	+	+					Peroneal 35	1.2	Peroneal 43/radial 43	20/22	I/II	+		No	No
13	M			+				Peroneal 39	0.8	Peroneal 42	24	II	+		No	No
14	M	+	+		+	+		Peroneal 43	1.6	Peroneal 44	12	II	+	+	No	No
15	M	+				+		Peroneal 40	1.0	Peroneal 42	7	II	+		No	No

^aType of neurological lesion. ^bRecruitment (muscular contraction): 0, absent; 1, simple; 2, weak intermediate; 4, rich intermediate. Recruitment data not available for patients 4, 8 and 12. CMAP, compound muscle action potential; CV, conduction velocity; FP, fibrillation potentials; LP, slow potentials of denervation; M, myopathy; N, neuropathy; NM, neuromyopathy.

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