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Table 2 Clinical and infectious characteristics of all patients with an ICU LOS of more than24 hours

From: Brazilian Sepsis Epidemiological Study (BASES study)

Characteristic Center 1 Center 2 Center 3 Center 4 Center 5 Total
Enrolled patients (n) 359 146 125 76 178 884
Median age (IQR) 73.6 (58.5–81.5) 55.4 (42.5–60.6) 47.6 (32.0–66.9) 61.4 (44.2–68.7) 68.9 (57.8–77.1) 66.4 (49.2–77.1)
Male/female (%) 62/38 59/41 59/41 62/38 51/49 59/41
Median APACHE II score (IQR) 16 (11–21) 17.5 (9.7–25.2) 16 (12–20) 16 (10–20) 18 (14–21) 17 (11–22)
First-day SOFA score (IQR) 3 (1–5) 6 (2.7–9) 6 (3–8) 4 (2–7) 6 (4–9) 4 (2–8)
Median ICU LOS, days (IQR) 3 (2–7) 5.5 (3–10.2) 6 (3–12) 3 (2–7.7) 4 (2–10) 4 (2–9)
Main ICU admission diagnosis       
   Respiratory infection, n (%) 43 (11.9) 16 (10.9) 10 (8.0) 12 (15.8) 42 (23.6) 123 (13.9)
   Acute coronary syndrome, n (%) 52 (14.5) 24 (16.4) 4 (3.2) 25 (32.9) 2 (1.1) 107 (12.0)
   GI postoperative patients, n (%) 9 (2.5) 11 (7.5) 5 (4.0) 7 (9.2) 50 (28.1) 82 (9.3)
   Sepsis, n (%) 34 (9.5) 2 (1.4) 17 (13.6) 3 (3.9) 13 (7.3) 69 (7.8)
   GI surgery for neoplasm, n (%) 22 (6.1) 4 (2.7) 4 (3.2) 7 (9.2) 25 (14.0) 62 (7.0)
   Cardiovascular surgery, n (%) 38 (10.6) 1 (0.06) 4 (3.2) - 18 (10.1) 61 (6.9)
   Clinical neurological disorders, n (%) 36 (10.0) 10 (6.8) 6 (4.8) - 5 (02.8) 57 (6.4)
Site of infection       
   Lung, n (%) 86 (72.3) 30 (43.5) 52 (67.5) 24 (68.5) 75 (70.1) 267 (65.6)
   Urinary tract, n (%) 9 (7.6) 4 (5.7) 5 (6.5) - 5 (4.7) 23 (5.6)
   Abdomen/surgical wound, n (%) 4 (3.3) 5 (7.3) - 5 (14.3) 6 (5.6) 20 (4.9)
   Bloodstream, n (%) 5 (4.2) 1 (1.5) 1 (1.3) 3 (8.6) 21 (19.6) 10 (2.5)
   Other/unknown, n (%) 15 (12.6) 29 (42.2) 19 (24.7) 3 (8.6) 21 (19.6) 87 (21.4)
   Diagnosed infections, n (%) 119 (100) 69 (100) 77 (100) 35 (100) 107 (100) 407 (100)
Enrolled patients, n       
   Consensus Conference Diagnosis 359 146 125 76 178 884 (100%)
   SIRS 291 130 122 74 168 785 (88.8%)
   Sepsis 121 72 79 34 109 415 (46.9%)
   Severe sepsis 57 38 46 191 81 241 (27.3%)
   Septic shock 42 34 39 16 72 203 (23.0%)
Overall mortality rate (%) 12.5 32.2 23.7 24.8 31.4 22.3
  1. GI, gastrointestinal; IQR, interquartile range; LOS, length of stay; SIRS, systemic inflammatory response syndrome; SOFA, sequential organ failure assessment.