Table 1 Procalcitonin (PCT), C-reactive protein (CRP), lactate and sepsis score values at different categories of the sequential organ failure assessment (SOFA) score and severity of systemic inflammation according to American College of Chest Physicians/Society of Critical Care Medicine (ACCP/SCCM) criteria

Category of SOFA score (number of observations)

   1–6 (n = 557)

3 (2/5)

0.37 (0.12/1.2)

101 (53/161)

1.24 (0.96/1.6)

6 (3/10)

   7–12 (n = 156)

9 (7/10)

2.55 (0.85/9.95)

140 (65/209)

1.74 (1.2/2.43)

13 (10/16)

   13–18 (n = 31)

14 (13/15)

8.5 (3.3/28.4)

180 (115/219)

3 (2.34/3.83)

21.5 (16.25/25.75)

   19–24 (n = 13)

19.5 (19/20)

23.24 (2.28/50.92)

154 (9.6/308)

3.7 (3.5/5)

25(24.25/25.75)

Category according to ACCP/SCCM criteria (number of patients)

   No SIRS (n = 15)

3 (2–4.5)

0.14 (0.07–0.29)

72 (20–125)

1.26 (0.64–1.38)

3 (0–5.5)

   SIRS (n = 15)

4 (2.25–8.25)

0.38 (0.16–0.93)*

51 (19.5–80.5)

2.13 (1.14–2.93)*

3.5 (2–8.25)

   Sepsis/SS (n = 71)

6 (4–9)

3 (1.48–15.26)**

164 (75–222)**

2.2 (1.27–3.74)

11 (7–17)**

   Sepsis (n = 34)

4.5 (3–6)

1.58 (0.41–3) **

150 (71–209)**

1.37 (1–2.61)

8.5 (3.75–12.25)**

   Severe sepsis (n = 22)

7 (6–8.25)^†

5.58 (1.84–32.93)^†

159 (75–209)

2.19 (1.73–2.93)

14.5 (9.25–19.75)^†

   Septic shock (n = 15)

11 (9–15)d

13.1 (6.1–42.2)^‡

195 (75–272)

3.7 (2.6–6.4)^‡

15 (13.5–19.5)

Trauma patients (n = 49)

5 (3–8)

1.4 (0.3–5.1)

40 (16–150)

2.7 (1.7–5)

3 (0–5.3)