Table 4 APACHE II and SOFA scores, cytokine levels, gastric intramucosal pH and gastric intramucosal carbon dioxide tension
Variable | Baseline | Immediately after NAC infusion | 24 hours after NAC infusion | 48 hours after NAC infusion |
|---|---|---|---|---|
APACHE II score | ||||
NAC | 13.14 ± 3.79 | - | 13.33 ± 3.83 | 12.74 ± 3.87 |
Control | 15 ± 3.58 | - | 15.34 ± 3.30 | 15.69 ± 3.4 |
SOFA score | ||||
NAC | 5.62 ± 2.52 | 5.55 ± 2.04 | 5.48 ± 2.57 | 5.48 ± 2.7 |
Control | 6.53 ± 2.2 | 6.92 ± 2.59 | 7.15 ± 2.9 | 7.15 ± 2.86 |
Tumour necrosis factor-α (pg/ml) | ||||
NAC | 25.58 ± 15.8 | 26.02 ± 16.1 | 22.68 ± 13.9 | 28.17 ± 26.8 |
Control | 22.57 ± 28.2 | 24.90 ± 13.56 | 25.05 ± 21.8 | 28.25 ± 24.3 |
IL-1β (pg/ml) | ||||
NAC | 6.68 ± 1.85 | 6.38 ± 1.07 | 5.91 ± 1.26 | 5.57 ± 1.62 |
Control | 5.35 ± 1.32 | 5.09 ± 0.30 | 5.34 ± 1.01 | 5.11 ± 0.58 |
IL-2 receptor (U/ml) | ||||
NAC | 1847 ± 1366 | 1918 ± 1450 | 1829 ± 1427 | 1816 ± 1806 |
Control | 2288 ± 1503 | 2372 ± 1531 | 2382 ± 1599 | 2168 ± 843 |
IL-6 (pg/ml) | ||||
NAC | 100.26 ± 88 | 100.22 ± 19.8 | 110.51 ± 37 | 100.38 ± 38 |
Control | 115.85 ± 85 | 115.64 ± 19.8 | 113.86 ± 27 | 119.48 ± 38 |
IL-8 (pg/ml) | ||||
NAC | 161.50 ± 55 | 161.6 ± 10.3 | 162.1 ± 12.4 | 168.8 ± 113 |
Control | 172.95 ± 27 | 163.3 ± 28.4 | 169.6 ± 28.6 | 171.0 ± 31 |
Gastric intramucosal pH | ||||
NAC | 8.41 ± 0.21 | 8.43 ± 0.22 | 8.43 ± 0.17 | - |
Control | 8.26 ± 0.18 | 8.31 ± 0.16 | 7.45 ± 0.47 | - |
Gastric intramucosal carbon dioxide tension (mmHg) | ||||
NAC | 67.2 ± 20.1 | 70.2 ± 15.6 | 69.0 ± 21.9 | - |
Control | 68.7 ± 22.8 | 69.7 ± 23 | 68.9 ± 25.7 | - |