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Impact of enteral feeding on gastric tonometry in ICU patients


This study investigates the impact of jejunal and gastric feeding on gastric mucosal pCO2 (PiCO2) in ICU patients.

Patients and methods

Seven stable mechanically ventilated ICU patients receiving ranitidine were studied. Nasojejunal and pHi nasogastric tubes were inserted and piCO2 measured with air tonometry. Jejunal (J) and gastric feeding (G) was performed in 1 h intervals as follows (period 1–9): 1 = baseline; 2 = J 40 ml/h; 3 = J 100 ml/h; 4 = no feeding; 5 = G 40 ml/h; 6 = G 100 ml/h; 7 = G bolus 200 ml; 8 = gastric emptying; 9 = no feeding.

Values are provided as means ± SD. ANOVA for repeated measures and Wilcoxon test were used for statistical analysis; P < 0.05 was considered significant.


Patients remained stable during the study. Baseline pCO2 gap (piCO2-paCO2) was 1.91 ± 0.66 kPa and did not change during the study (ANOVA P = 0.44; Fig. 1)

Marked interindividual variability was observed during gastric feeding mainly.

figure 1



In ICU patients jejunal feeding does not influence piCO2. The effect of gastric feeding is much less predictable and needs to be tested in each patient.

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Rokyta, R., Šrámek, V., Novák, I. et al. Impact of enteral feeding on gastric tonometry in ICU patients. Crit Care 2 (Suppl 1), P136 (1998).

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