Volume 2 Supplement 1
Variations of veno-arterial and mucosal-arterial CO2 gap during continuous veno-venous hemodiafiltration
© Current Science Ltd 1998
Published: 1 March 1998
Veno-arterial CO2 gap (P(v-a) CO2) and mucosal-arterial CO2) gap (P(g-a) CO2 may help to detect tissular dysoxia. Continuous veno-venous hemodiafiltration (CVVHD) technics are well tolerated in septics patients.
Change of P(v-a) CO2 and of P(g-a) CO2 during CVVHD.
Prospective study. Intubated and ventilated patients. Hemodynamics and systemic oxygen derived parameters were collected before and during CVVHD (H0-H6). CVVHD setting parameters (PRISMA®, HOSPAL) were standardised. Gastric mucosal PCO2 continously monitored (NGS (TONOMETRICS) and TONOCAP® (DATEX). P(v-a) CO2 and P(g-a) CO2 calculated. Continuous measure of end tidal CO2 (PetCO2). Statistics: ANOVA, Scheffe t test for paired and unpaired values
The marked increase of P(g-a)CO2 during CVVHD could be explained by acid-base status in the mucosa independent of hemodynamics changes.