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Figure 3 | Critical Care

Figure 3

From: Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]

Figure 3

The time course of biomarkers of thrombin generation and fibrinolysis in placebo-treated patients with severe sepsis in the PROWESS study are shown here as means and 95% confidence intervals, using standard error of the mean and repeated measures analysis without imputing for missing data. The number of observations for each time point appears below the x-axis for (●) survivors and (○) nonsurvivors. *P < 0.05 versus nonsurvivors. F1.2, prothrombin fragment 1.2; PAI, plasminogen activator inhibitor; TAFI, thrombin-activatable fibinolysis inhibitor; TAT, thrombin–antithrombin complex.

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Critical Care

ISSN: 1364-8535