Following severe injury, hypocholesterolemia improves with convalescence but persists with organ failure or onset of infection

Table 2 Cholesterol values, as a percentage of expected cholesterol, and organ/metabolic dysfunction relationships

Condition	% Cholesterol without condition	% Cholesterol with condition	P
Creatinine > 2.0 mg/dl	68 ± 21	55 ± 13	0.0001
Bilirubin > 2.5 mg/dl	68 ± 21	60 ± 21	0.0006
Bicarbonate ≥ 28 or ≤ 23 mmol/l	71 ± 22	63 ± 19	0.0001
PaO₂/FiO₂ < 350	74 ± 21	65 ± 20	0.0001
Glucose > 120 mg/dl	69 ± 19	65 ± 23	0.009

% Cholesterol is the cholesterol value as a percentage of expected cholesterol. Values are expressed as mean ± standard deviation. FiO₂, fractional inspired oxygen; PaO₂, arterial oxygen tension.

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