Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury

Table 1 Description of the different methods used in experimental and human studies to perform recruitment maneuvers

Methods	Study	References
Continuous positive airway pressure at 30–60 cmH₂O for 15–60 s	Saline lavage, oleic acid, and pneumonia in animals	[15–20, 54]
Pressure controlled mode: peak inspiratory pressure at 60 cmH₂O and end-expiratory pressure at 40 cmH₂O for 2 min	Saline lavage in animals	[18, 20]
Volume controlled mode: 20 breaths at tidal volume of 20 ml/kg	Anesthetized healthy animals	[21]
Continuous positive airway pressure at 30–45 cmH₂O for 15–20 s	Anesthetized healthy patients	[23, 26]
Pressure controlled mode: peak inspiratory pressure at 30–40 cmH₂O and end-expiratory pressure at 10–20 cmH₂O for 1 min	Anesthetized healthy patients	[24, 25, 27]
Sighs with a tidal volume to reach 45 cmH₂O plateau pressure	ARDS patients	[29, 40]
Continuous positive airway pressure at 30–45 cmH₂O for 4–40 s	ALI/ARDS patients	[30, 32, 38, 39]
Extended sigh with a tidal volume to reach 40 cmH₂O and end-expiratory pressure at 35 cmH₂O for 1 min	ARDS patients	[31]
Pressure controlled mode: peak inspiratory pressure at 40–60 cmH₂O and end-expiratory pressure at 10–30 cmH₂O for 30–120 s	ARDS/brain injury patients	[33, 36, 37]
Pressure support mode: peak inspiratory pressure at 40 cmH₂O and end-expiratory pressure for 30 s	ALI/ARDS patients	[35]

ISSN: 1364-8535