Reducing mortality in sepsis: new directions

Table 4 Outcome measures: percentage change or improvement, baseline to 72 hours

Outcome measure	Control	Treatment	P value
ScvO₂ *	32.7	44.9	0.001
Lactate*	43.5	61.0	0.02
Base deficit*	42.7	77.5	0.001
pH*	5.4	12.3	0.001
APACHE II*	24.5	40.2	0.002
Mortality in hospital	46.5	30.5	0.009
Mortality at 28 days	49.2	33.3	0.01
Mortality at 60 days	56.9	44.3	0.03
Length of hospital stay^†	-	20.7	0.04

APACHE II, Acute Physiology and Chronic Health Evaluation; ScvO₂, central venous oxygen saturation. * Baseline to 72 hours. ^†Surviving to hospital discharge.

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