Table 1 Neutrophil and endothelial cell adhesion receptors

L-selectin

Neutrophil

sLe^a, sLe^x

Endothelium

Rolling and weak adhesion of PMNs on EC

CD11a/CD18

Neutrophil

ICAM-1, ICAM-2, ICAM-3

Endothelium

Adhesion of PMNs on EC

CD11b/CD18

Neutrophil

ICAM-1

Endothelium

Adhesion of PMNs on EC

iC3b

Complement

Phagocytosis?

Fibrinogen

-

-

Factor X

-

-

CD11c/CD18

Neutrophil

iC3b

Complement

Phagocytosis?

Fibrinogen

-

-

E-selectin

Endothelium

sLe^x

Neutrophil

Firm PMN/EC adhesion

P-selectin

Endothelium, platelets

sLe^x

Endothelium

Firm PMN/EC adhesion

PSGL-1

Neutrophil

Firm PMN/EC adhesion

PECAM-1

Endothelium

CD31/

Leukocytes

Diapedesis of PMN through EC

αv

Neutrophil

-

-

ICAM-3

Neutrophil

CD11a/CD18

Leukocytes

Antigen presentation