Figure 2

Neutrophil apoptosis pathways. Note that Fas, FADD, and FLICE are also known as APO-1, MORT-1, and MACH, respectively. FADD, Fas-associated death domain; FasL, Fas ligand; FLICE, FADD-like IL-1β converting enzyme (ICE); IAP, inhibitor of apoptosis protein; NF-κB, nuclear factor-κB; TNFR, tumor necrosis factor receptor; TRADD, TNFR-associated protein death domain; TRAF, TNFR-associated factor.