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Table 2 Summary of studies of gastrointestinal promotility drugs

From: Prokinetic agents in critical care

Study design

Number of studies

Population (n)

Tube placement studies (examining the role of prokinetics in aiding transpyloric intubation)

6

351

Patient outcome studies (examining pneumonia and mortality or gastric and pulmonary colonization)

2

330

Studies that examined the effects of the prokinetic agents on gastrointestinal transit and feeding intolerance

  

   Cisapride versus placebo

4

147

   Erythromycin versus placebo*

2

30

   Metoclopramide versus placebo*

2

26

   Metoclopramide versus cisapride*

1

14

   Metoclopramide versus erythromycin and cisapride*

1

10

  1. *Studies of agents that are available as prokinetics in contemporary practice.
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Critical Care

ISSN: 1364-8535