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Table 1 Sieving coefficients of large pore membranes and conventional pore membranes

From: Hemofiltration, adsorption, sieving and the challenge of sepsis therapy design

  

Cytokine

Membrane

Operating characteristics

IL-8 (MW = 8 kDa)

TNFα (MW = 17 kDa)

IL-1 (MW = 17 kDa)

IL-10 (MW = 17 kDa)

IL-6 (MW = 26 kDa)

Albumin (MW = 69 kDa)

100 kDa polyamide [20]

1 l/h

0.31

0.27

0.81

0. 56

0.73

0.06

 

6 l/h

0.19

0.09

0.75

0. 56

0.32

0.0

Polyamide* [21]

Variable

0.25

0

0.18

 

0

 

Polysulfone* [22]

 

0.12

0.22

0.42

0

0.04

 

AN69** [23]

 

0.08

0.16

0.22

0

0.18

 
  1. TNFα, tumor necrosis factor alpha; MW, molecular weight. Mean molecular weight cut-off (MWCO) of 30 kDa is shown in the table by the sign * and the MWCO of 50 kDa is shown in the table by the sign **.
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Critical Care

ISSN: 1364-8535