Figure 4
Effect of lipopolysaccharide (LPS) on ileal mucosal O2 consumption. Rats in the NS/NS group were injected at T = 0 hours with normal saline (NS) and were treated with NS. Rats in the LPS/NS group were injected with LPS (5 mg/kg) at T = 0 hours and were treated with NS. Rats in the LPS/AG group were challenged with the same dose of LPS and treated with aminoguanidine (30 mg/kg per dose at T = 1, 3 and 6 hours). Ex vivo O2 consumption was measured at T = 8 hours. Adapted from [24] with permission.