Figure 2

Comparison of death rates between patients given ATIII and patients given placebo in the four RCTs that met the inclusion criteria of out meta-analysis. The odds ratios of the individual studies and of our meta-analysis are denoted by dots and by a diamond, respectively; each horizontal bar indicates the 95% CI for the odds ratio, and the vertical dotted line represents the identity line. From top to bottom, datasets are the trials of Warren et al. [10], Baudo et al. [8], Eisele et al. [9], and Fourrier et al. [7]; the bottom dataset is our meta-analysis. In the four RCTs, the crude death rates in the treatment group and in the control group, respectively, were as follows: Fourrier et al. [7], 7 of 17 versus 9 of 18; Eisele et al. [9], 5 of 20 versus 9 of 22; Baudo et al. [8], 31 of 50 versus 33 of 48; Warren et al. [10], 450 of 1157 versus 448 of 1157.