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Figure 4 | Critical Care

Figure 4

From: Bench-to-bedside review: Lactate and the kidney

Figure 4

Changes in the concentration of lactate, bicarbonate (HCO3), base excess (BE) and chloride (Cl) after a patient with septic shock was placed on high-volume hemofiltration (HVHF) and received an infusion of 240 mmol/hour lactate. The acidifying effect of hyperlactatemia (fall in bicarbonate and in base excess) was markedly attenuated by a decrease in serum chloride concentration (chloride shift). At the end of 8 hours of HVHF, there was a rebound alkalosis.

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Critical Care

ISSN: 1364-8535